Personalized prescriptions with the RightMed® Solution
Co-developed with Mayo Clinic, OneOme’s RightMed Solution helps doctors and pharmacists across the globe offer patients more personalized medication therapy.
The RightMed Comprehensive Test
The RightMed Comprehensive Test is a pharmacogenomic (PGx) test that analyzes an individual’s DNA to help doctors and pharmacists determine how he or she may respond to certain medications. The test covers hundreds of medications used to treat a wide range of medical conditions, including cancer, psychiatric conditions, chronic pain, cardiovascular disease, and more.
The RightMed Comprehensive Test Report
Results are compiled into our RightMed Comprehensive Report, which contains genotype/phenotype information for 27 genes, as well as information on each of the 300+ medications covered by the test.
Medications covered
The RightMed Comprehensive Test covers hundreds of commonly prescribed medications, including metoprolol (Lopressor), citalopram (Celexa), pantoprazole (Protonix), escitalopram (Lexapro), atorvastatin (Lipitor), tramadol (Ultram), duloxetine (Cymbalta), codeine, clopidogrel (Plavix), and amitriptyline (Elavil).
Medical conditions
The RightMed Comprehensive Test provides results for medications used to treat many medical conditions.
This breadth in coverage brings value to healthcare institutions by matching their diverse specialty needs while empowering their providers to prescribe with more confidence.
View full list of medical conditions
- Acute migraine
- ADHD
- Allergies
- Alzheimer's disease
- Anticoagulation
- Antiplatelet therapy
- Anxiety
- Arrhythmias
- Bacterial infection
- Benign prostatic hyperplasia
- Cancer
- Chronic hepatitis C
- Depression
- Diabetes
- Dyslipidemia
- Fungal infection
- Gastroesophageal reflux disease
- Gout
- HIV infection
- Hypertension
- Immunosuppression
- Migraine prophylaxis
- Overactive bladder
- Pain
- Parkinson's disease
- Psychosis
- Rheumatoid arthritis
- Seizures
- Sleep disorders
- Smoking cessation
Genes covered
The RightMed Comprehensive Test provides information on 27 genes based on OneOme’s rigorous standards of pharmacogenomic evidence.
| Gene | Alleles |
|---|---|
| CYP1A2 | *1C, *1D, *1E, *1F, *1J, *1K, *1L, *1V, *1W |
| CYP2B6 | *4, *5, *6, *7, *9, *16, *18 |
| CYP2C Cluster | G/A (rs12777823) |
| CYP2C9 | *2, *3, *4, *5, *6, *8, *11 |
| CYP2C19 | *2, *3, *4, *4B, *10, *17 |
| CYP2D6 | *2, *2A, *3, *4, *4J, *4K, *4M, *4N, *5, *6, *6C, *7, *8, *9, *10, *11, *12, *13, *14, *15, *17, *18, *19, *29, *31, *34, *35, *36, *39, *41, *42, *59, *61, *63, *64, *65, *68, *69, *70, *91, *109, *114, copy number variations |
| CYP3A4 | *1B, *22 |
| CYP3A5 | *3, *6, *7 |
| CYP4F2 | *3 |
| COMT | Val158Met (rs4680) |
| DPYD | *2A, Asp949Val, *13 |
| DRD2 | -241A>G (rs1799978) |
| F2 | 20210G>A (rs1799963) |
| F5 | Arg534Gln (Leiden, 1691G>A) |
| GRIK4 | Intronic T>C Variant (rs1954787) |
| HLA-A | HLA-A*31:01 |
| HLA-B | HLA-B*15:02, HLA-B*57:01, HLA-B*58:01 |
| HTR2A | Intron 2, T>C Variant (rs7997012) |
| HTR2C | -759C>T (rs3813929) |
| IL28B (IFNL4) | Intronic C>T Variant (rs12979860) |
| MTHFR* | 677C>T (rs1801133); 1298A>C (rs1801131) |
| NUDT15 | Arg139Cys (rs116855232) |
| OPRM1 | Asn40Asp (rs1799971) |
| SLC6A4 | -1936A>G (rs25531); -1917_-1875del43 (rs774676466) |
| SLCO1B1 | *1B, *5, *15, *17, *21 |
| TPMT | *2, *3A, *3B, *3C, *4 |
| UGT1A1 | *6, *28 (TA7) |
| VKORC1 | -1639G>A (rs9923231); 442C>T (rs7200749) |
NOTE: The test does not detect all known and unknown variations in the gene(s) tested. For drug metabolizing enzyme, the absence of a detectable variant (designated as *1) does not rule out the presence of other variants not tested.
*MTHFR is available for providers to order as an optional, complimentary add-on to the RightMed Test.
Technology & support
In addition to the RightMed Comprehensive Test, OneOme offers doctors and pharmacists technology and support to help them implement PGx in their practices.
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Vantage™
Doctors and pharmacists have access to Vantage, a tool that provides online access to clinical decision support, allowing users to easily interpret the patient’s test results. It includes capabilities to search, filter, and select medications, view detailed information about medications, identify alternative medications, explore drug-to-drug interactions, and generate customized reports.
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Clinical consultations
Doctors and pharmacists can get help interpreting their patients’ RightMed results by consulting with our PGx experts. Clinical consultations are complimentary for OneOme customers.
Evidence-based pharmacogenomics
Scientific evidence and clinical rigor are cornerstones of the RightMed Comprehensive Test.
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CAP/CLIA Certified Lab
OneOme’s in-house lab, located alongside our corporate headquarters in Minneapolis, MN, is certified by both CAP and CLIA.
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Data Curation
The relationships between the medications and pharmacogenes annotated in our database are supported by scientific evidence that meets OneOme’s rigorous inclusion criteria. (Published September 2020.)
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PGx guidelines
OneOme’s team of pharmacists and scientists use professional guidelines to guide their data curation.
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Get started today
learn more or to get started with PGx in your health system, please contact us.